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Spotlight
Structure and function of a fungal AB toxin-like chimerolectin involved in anti-nematode defense
A recent "EMBO J" paper by the Künzler group (IMB) in collaboration with the Krengel group at University of Oslo (UiO) reports on a new class of fungal nematotoxins that shows structural and functional similarity to bacterial and plant AB toxins.
Inflammation shapes tolerance: CD8 T Cell Sensing of Type I Interferon Impacts Anergy
A study by the Oxenius group (IMB) published in the "European Journal of Immunology" reveals that baseline inflammation limits the induction of T cell tolerance. Basal IFN-I allows self-reactive T cells to expand and retain partial effector functions, linking baseline inflammation to autoimmunity.
Jörn Piel receives "Research Award of the Leibniz Research Network Bioactive Compounds"
Jörn Piel, Professor for Bacterial Natural Product Research at the Institute of Microbiology has been awarded for his pioneering work on bioactive natural products produced by bacteria
Beyond serology: unveiling the genetic blueprint of Escherichia coli’s outermost defense
Researchers from the Slack and Sunagawa groups presented a new tool - kTYPr - to map capsule serotypes in E. coli genomes. The study, published in Nature Microbiology, revives E. coli capsule research, revealing unprecedented genetic and ecologic diversity of these key virulence determinants.