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Spotlight
An endangered natural pharmacy hidden in coral reefs
Researchers at ETH Zurich have identified hundreds of microbial species living among corals. These microbes produce a variety of substances with untapped potential for medicine and biotechnology, making the reef ecosystem even more valuable than previously recognised.
New Paper in Chem by the Piel Lab and the Sunagawa Lab
Widespread hypermodified β-helical peptides in common bacteria
New Paper in PLOS Pathogens by the Hardt Lab
TTSS-2 virulence drives inflammatory destruction of the gut epithelial barrier and modulates inflammatory response profiles in the Salmonella-infected mouse gut
Reducing carbon loss during bioconversion of CO2-derived methanol
Formate accumulation limits bioproduction from CO₂-derived methanol. Keller and Hegedis et al. discovered that NAD-dependent methanol dehydrogenases overoxidize methanol to formate—and found non-overoxidizing variants that have the potential to boost process yields.